Los Angeles, September 12
Researchers have developed an intranasal anti-viral treatment for Covid-19 that decreases the amount of SARS-CoV-2 shed from infected animals and limits transmission of the virus.
Historically, it has been exceptionally challenging for antivirals and vaccines to limit the transmission of respiratory viruses, including SARS-CoV-2. Leor Weinberger, senior author of the new research
By the time people test positive for Covid, the SARS-CoV-2 virus has already taken up residence in their respiratory system. With each breath, people expel invisible viral particles into the air — a process known as viral shedding. Existing drugs aimed at treating Covid address symptoms of the virus but do little to quell viral shedding.
Researchers at Gladstone Institutes in the US previously developed a novel approach for treating infectious diseases: a single-dose, intranasal treatment that protects against severe SARS-CoV-2 infection. In a study published in journal Proceedings of the National Academy of Sciences, they show that this treatment, called a therapeutic interfering particle (TIP), also decreases the amount of virus shed from infected animals and limits transmission of the virus. Gladstone investigator Leor Weinberger, senior author of the new research, said: “This study shows that a single, intranasal dose of TIPs reduces the amount of virus transmitted, and protects animals that came into contact with that treated animal.”
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2022-09-13 03:22:00Z
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